Opportunities for Harold Hamm Diabetes Center members include funding awards
and access to
core facilities. A variety of funding awards are available to members to encourage the
further development of their work. Award applications are evaluated on
a competitive, peer-reviewed basis by the Harold Hamm Research Grants
Committee and External Review Panel. Additional awards, such as matching
awards to other funding opportunities, will be announced if they become
available.
Spring 2023 Award Opportunities
Funding Opportunity Summary
The Harold Hamm Diabetes Center (HHDC) is pleased to announce pilot funding
opportunities for 2023. The HHDC Pilot Program will consider funding six
types of proposals including Team Science proposals, Pre-Team Science
proposals, Novel Pilot Projects, Novel Pilot Projects for Post-Docs, Bridge
Funding, Equipment grants and a Travel Stipend. Based on a matching gift,
the HHDC will award up to $1.6M to researchers to launch investigations
for Diabetes research. These funds will be augmented with a collaboration
with the Stephenson Cancer Center for projects specifically aimed at collaboration
between researchers in diabetes and cancer.
Key Information
HHDC FUNDED PROGRAMS:
Team Science Grant: $100,000 per year up to 3 years
Novel Pilot Project Grant: $70,000 for up to 2 years
Novel Pilot Project Grant for Post-Docs: $70,000 per year for up to 2 years
Bridge Grant: $100,000 for 1 year
Equipment Grant: Up to $250,000
Travel Stipend: Up to $2,500
HHDC-SCC FUNDED PROGRAMS:
Team Science Grant: $100,000 per year up to 3 years
Novel Pilot Project Grant: $70,000 per year for up to 2 years
Funding Priorities:
Applications should be closely aligned with the mission of the HHDC to
increase understanding about the causes and consequences of diabetes and
closely related cardiometabolic conditions like obesity, liver disease,
and cancer, as well as strategies for prevention or treatment of these
conditions. Additionally, proposals that address one or more of the following
themes are HHDC funding priorities:
Theme 1: Diabetes and Obesity Across the Lifespan. Proposals that aim to gain basic science and clinical knowledge on the
inter-relationship of obesity and diabetes across the lifespan. For example:
Genetic, epigenetic, and environmental basis of susceptibility to developing
insulin resistance, metabolic dysregulation, inflammation, macrovascular
and microvascular diabetic complications, or obesity across the lifespan.
Theme 2: Pancreas and Beta Cell Function. We encourage investigators interested in all aspects of pancreatic function
in type 1, type 2, or gestational diabetes and associated conditions to
submit their research proposals in this area. This includes studies that
utilize pancreatic tissue samples, relevant cell culture and animal models,
and human-based studies of in-vivo and ex-vivo pancreatic function. Some
examples include:
Physiology and mechanisms for insulin and c-peptide production, secretion,
or action; modulation of pancreatic function with obesity, diabetes, aging,
or related conditions.
Strategies to modulate, maintain, or restore insulin secretion in the presence
of diabetes, pre-diabetes, or during the aging process.
Genetic, autoimmune, or environmental processes leading to reduction in
beta cell mass or function.
Studies of the action of pancreatic-derived proteins such as glucagon,
somatostatin, or digestive enzymes, especially if the intent is to understand
the metabolic causes and consequences of obesity or diabetes.
If your research could benefit from use of human pancreatic samples, please
contact us about opportunities to acquire these tissues locally.
Theme 3: Diabetes/Obesity and Cancer. Proposals that aim to answer questions about the relationship surrounding
obesity, diabetes, and cancer. Some examples include:
Mechanisms through which obesity and/or diabetes and co-morbidities promote
cancer risk, or progression to lethal disease. Successful applications
will leverage basic science tools across disease models to address a transdisciplinary problem.
The impact of cancer therapies or cancer growth on metabolic health in
basic, preclinical, or clinical studies. Successful applications will
evaluate long term effects of physiologically relevant cancer treatments
on issues such as diabetes risk, cachexia, neurodegeneration, or other
adverse outcomes.
Disparities in obesity/diabetes or cancer risk/prognosis that associate
with poor health outcomes in one of these areas (e.g., in obesity-associated
cancers). Successful applications will explore the social, economic, or
individual contributors to those inequalities.
COVID-19 Related Proposals Proposals studying Covid-19 are welcome if they are related to the HHDC
mission, e.g. exploring the relationship between diabetes and Covid-19
presentation or outcomes, and there is a plan for follow-on studies by
applying for extramural funding.
Eligibility The PI of any HHDC grant application must be a Member of HHDC; the co-investigators
(Multi-PI) do not have to be members at the time of application but if
successful are required to become Members or Associate Members of HHDC
during the tenure of the grant. Grant recipients may not apply for or
hold another HHDC grant or Team Science grant as project PI or MPI.
Application Process
LETTER OF INTENT Letter of Intents are due to
HHDCGrants@ouhsc.edu by
5 p.m. on January 16, 2023. Applications selected for full application submission will be notified
by February 6, 2023. The projected start date for the award will be July 1, 2023.
LOIs are due January 16, 2023, by 5:00 p.m.,and must include a Face Page (Template Provided), which includes the following:
Investigator(s)' NIH Biosketches
Personal Statement
Project Title
Project Summary
Project Specific Aims
FULL APPLICATION Application attachments will vary by proposal type. Please see grant specific
instructions below for further information.
For all applications, the sponsored programs grant routing form and completed
application must be received by ORA at least three business days prior to the
March 17, 2023 grant application deadline. You must submit an electronic routing form using
SoonerTrack. A copy of the application must be attached to the SoonerTrack ticket
or emailed for review to your Sponsored Program Administrator. Once the
review is complete, the Face Page of the grant application must be signed
by the ORA official before the PI submits the final application to HHDC.
Note: External Applicants will need to use their own institution’s
offices for any grant processing, and comply with the March 17, 2023 HHDC
grant application deadline above.
SUBMISSION AND REVIEW OF FINAL APPLICATION Send the final application by e-mail to
HHDCGrants@ouhsc.edu no later than 5 p.m. on Friday,
March 17, 2023. Please title the application attached to the email: HHDC <Type of Grant>
Grant-[PI Last Name, First Name].
Please submit the application as a single file in pdf format. Failure to follow these steps could cause your application to be overlooked
and not reviewed by the HHDC Grants Review Committee.
For 2023 and onward, the HHDC Grants Review Committee will review and award
grants in consultation with two outside reviewers. Outside reviewers will
be specifically selected for each application, for their relevant subject
matter expertise. Applicants are encouraged to provide the names of two
potential outside reviewers in their LOI. Final selection of the two outside
reviewers will be made by the HHDC Grants Review Committee. Once appointed,
the internal committee and two outside reviewers will evaluate the proposal
to come to a funding decision.
PROGRAM APPLICATION AND GUIDELINES All applications will follow the HHDC Application Form, Terms and Guidelines
found here:
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