Priya Balasubramanian, BVSc, PhD

  • Research Program: Geroscience
  • Position: Asst. Professor, Department of Biochemistry & Molecular Biology


"My research focuses on understanding the therapeutic potential of adipose tissue thermogenesis or increased cellular expenditure for age-related diseases, specifically vascular cognitive impairment, and sarcopenia. I'm interested in understanding the mechanisms mediating the beneficial effects of favorable remodeling of adipose tissue by thermogenic stimulation on systemic metabolism, inflammation, and microvascular endothelial function. Research efforts will also be focused on gleaning novel insights into the endocrine actions of adipose tissue secreted lipid bioactive molecules on the microvasculature in aging. Emerging evidence suggests that cancer survivors who underwent chemotherapy suffer from an early onset of age-related diseases indicating an accelerated aging phenotype. We will investigate how the hallmarks of aging can be targeted for accelerated aging in cancer survivors."



Health Education
  • Graduate School
  • Postdoctoral Training in Adipose Tissue Metabolism Wayne State University
  • Postdoctoral training in Aging and Metabolism University of Wisconsin-Madison
  • PhD in Pharmacology and Toxicology Michigan State University
    East Lansing, MI
  • Undergraduate School
  • Bachelor's Degree in Veterinary Science Madras Veterinary College, Chennai, India
Research Interests:
  • Understanding the role of endothelial senescence in age-related vascular cognitive impairment.
  • Targeting adipose tissue thermogenesis for vascular cognitive impairment in aging.
  • Mechanisms of accelerated aging in cancer survivors focusing on the long-term effects of chemotherapy.
  • Adipose-skeletal muscle crosstalk as a target for sarcopenia.
  • Obesity-induced cognitive impairment in older adults: a microvascular perspective 2021
  • Aging is associated with glial senescence in the brainstem - implications for age-related sympathetic overactivity 2021
  • Single-cell RNA sequencing identifies senescent cerebromicrovascular endothelial cells in the aged mouse brain 2020
  • Aging and Caloric Restriction Research: A Biological Perspective With Translational Potential 2017
  • Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic ß3-adrenergic receptor activation 2014