Priya Balasubramanian, BVSc, PhD

Biography

"My research focuses on understanding the therapeutic potential of adipose tissue thermogenesis or increased cellular expenditure for age-related diseases, specifically vascular cognitive impairment, and sarcopenia. I'm interested in understanding the mechanisms mediating the beneficial effects of favorable remodeling of adipose tissue by thermogenic stimulation on systemic metabolism, inflammation, and microvascular endothelial function. Research efforts will also be focused on gleaning novel insights into the endocrine actions of adipose tissue secreted lipid bioactive molecules on the microvasculature in aging. Emerging evidence suggests that cancer survivors who underwent chemotherapy suffer from an early onset of age-related diseases indicating an accelerated aging phenotype. We will investigate how the hallmarks of aging can be targeted for accelerated aging in cancer survivors."

Email

Priya-Balasubramanian@ouhsc.edu

Publications

Research Interests:

• Understanding the role of endothelial senescence in age-related vascular cognitive impairment.
• Targeting adipose tissue thermogenesis for vascular cognitive impairment in aging.
• Mechanisms of accelerated aging in cancer survivors focusing on the long-term effects of chemotherapy.
• Adipose-skeletal muscle crosstalk as a target for sarcopenia.