Kevin Short, PhD
- Position: Diabetes Research Member, Associate Professor, Department of Pediatrics
Biography
Dr. Short's training and experience in exercise physiology, endocrinology, and metabolism have directed his research interests toward identifying the most effective approaches to identify, prevent, and reverse cardiometabolic disease risk in children and young adults, thereby limiting a potential lifetime of pathology and medical burden. The studies use tests of exercise capacity, body composition, vascular function, and stable isotope tracers, and biochemical and molecular sample analyses. Dr. Short and his colleagues have experience with several tools to conduct detailed clinical and metabolic assessments of human subjects. Recent studies have examined how cardiometabolic risk factors are affected by obesity, type 1 and type 2 diabetes, and nonalcoholic fatty liver disease (NAFLD) in adolescents. NAFLD is a current area of emphasis. They are pursuing several gaps in our understanding about the disordered metabolism driving the pathophysiology of pediatric NAFLD in collaboration with Dr. Sirish Palle, who directs the pediatric NAFLD clinic. The number of patients in the pediatric NAFLD clinic are rapidly increasing, signifying the critical need to understand the pathology and treatment options for this disease in young people.
Additional Websites
- Graduate School
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Post-Doctoral Fellowship
Mayo Clinic
Rochester, MN -
Doctoral Studies
Ball State University
Muncie, IN -
Master's Degree
Purdue University
Lafayette, IN
- University
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Bachelors in Psychology with Research Honors
Illinois Wesleyan University
Bloomington, IL
- Exercise physiology
- Metabolism
- Endocrinology
- Obesity
- Diabetes
- Nonalcoholic fatty liver disease
- Pediatrics
Grant Funding
- Reducing sedentary time in favor of physical activity in adolescents HHDC Team Science grant. Co-PI with Darla Kendzor, PhD
- Evaluating microRNA-122 as a biomarker for non-invasive detection of non-alcoholic fatty liver disease in children, OSCTR pilot
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A pilot study of the effects of a high-intensity aerobic exercise session on heart rate variability and arterial compliance in adolescents with or without type 1 diabetes
2020
21: 486-495, 2020. PMID: 31951305
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Nutritional origins of pediatric non-alcoholic fatty liver disease: Molecular mechanisms and therapeutic targets
2020
12: 3166, 2020. PMID: 33081177 PMCID: PMC7602751.
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Effect of obesity and exercise training on amino acid metabolites in American Indian adolescents.
2019
J Clin Endocrinol Metab, Published online Apr 17, 2019.
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Using financial incentives to promote physical activity in American Indian adolescents: a randomized controlled trial.
2018
PLOS ONE, 13(6): e0198390
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A single exercise session increases insulin sensitivity in normal weight and overweight/obese adolescents.
2018
1050-1057, 2018. PMID: 29687558; PMCID: PMC6201285
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Overview of pediatric nonalcoholic fatty liver disease: a guide for general practitioners.
2018
111(8), 806-811, 2018. PMID: 31303681; PMCID: PMC6625810
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Glycemic variability is associated with markers of vascular stress in adolescents.
2016
J Pediatrics, 172: 47-55
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Oxidized HDL and LDL in adolescents with type 2 diabetes compared to normal weight and obese peers.
2015
J Diabetes Complications, 29:679-685
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Arterial compliance in children with obesity and T2DM: Implications for future cardiovascular health.
2014
Exerc Sports Sci Rev 42: 175-182
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Obese children have higher arterial elasticity without a difference in endothelial function: the role of body composition
2012
165-171, 2012. PMID:21996664
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Pigment epithelium-derived factor (PEDF) varies with body composition and insulin resistance in healthy young people
2012
E2114-2118, 2012. PMID 22930782; PMCID: PMC3485604