Jolyn Fernandes, MS, PhD
- Position: Diabetes Research Member
Biography
With a particular focus on metallomic and metabolomic strategies, the Fernandes lab uses diverse cellular and molecular integrated approaches to identify key molecular pathways that associate pre- and postnatal environmental exposures with offspring neurodevelopmental and metabolic disease susceptibility. Heavy metals are a risk factor for diabetes and metabolic dysregulation. As such a current focus in the Fernandes lab is to utilize high-resolution, high-throughput technologies to improve our understanding of the basis for differential disease susceptibility through early life nutritional and toxic metal exposures. Ultimately Dr. Fernandes lab aims to identify metabolic diagnostic biomarkers that could be developed for predictive therapeutic interventions in metabolic diseases.
- Graduate School
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Postdoctoral Fellow, Division of Pulmonary, Allergy, Critical Care and Sleep Medicine
Emory University School of Medicine
Atlanta, GA -
PhD, Biochemistry and Molecular Biology
University of Oklahoma Health Sciences Center
Oklahoma City, OK -
Masters, Biochemistry
The Institute of Science
Mumbai, India,
- University
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Bachelors in Microbiology and Biochemistry
St. Xavier's College
Mumbai, India,
Mitochondria environmental stress signaling networks
Emory University, Atlanta, GA
Establish integrated omics networks to study adaptive and maladaptive hubs in mitochondria-cell signaling system that are impacted by environmental agents like manganese contributing to neurological disorders.
Role: Post-Doctoral Scholar
(Enzymology, metabolomics, transcriptomics, redox-proteomics, metals, cellular redox, oxidative stress, antioxidant responses, molecular signaling, neuronal mitochondrial bioenergetics, bioinformatics)
PI: Dr. Dean P. Jones, Dr. Young-Mi Go Kang
http://grantome.com/grant/NIH/R21-ES025632-02S1
Cytoplasmic-nuclear redox signaling: Disruption by dietary cadmium levels.
Emory University, Atlanta, GA
Targeted evaluation of dietary Cd health risks studies in mice through global proteomic and transcriptomic analysis along calibrated Cd-dependent markers of inflammation and fibrosis wherein Cd exposures at levels found in the American diet adversely impacts the mechanisms of cytoplasmicnuclear cell signaling of inflammation and fibrosis.
Role: Post-Doctoral Scholar
(Enzymology, metabolomics, transcriptomics, redox-proteomics, metals, cellular redox, oxidative stress, bioinformatics)
PI: Dr. Dean P. Jones, Dr. Young-Mi Go Kang
http://grantome.com/grant/NIH/R01-ES023485-01A1
Identify maternal prenatal metabolic pathways and metabolite correlations that link environmental exposures and preterm birth in African-American women.
Center for Children's Health, the Environment, the Microbiome and Metabolomics, Nell Hodgson School of Nursing, Emory University
Role: Post-Doctoral Scholar
(metabolomics, bioinformatics, metadata driven workflow)
PI: Dr. Dean P. Jones, Dr. Betsy Corwin, Dr.Shuzhao Li
http://www.nursing.emory.edu/c-chem2/index.html
Enhanced cardiac fatty acid utilization induced by high dietary fat: a potential regulatory role for mitochondrial aconitase.
Modulation of mitochondrial function by pro-oxidants
Role: Graduate Research Assistant
(enzymology, proteomics, post-translational modifications, cardiac mitochondrial bioenergetics)
Jolyn Fernandes, MS, Ph.D.
PI: Luke I. Szweda, Michael Kinter
https://grantome.com/grant/NIH/R01-AG016339-09