Advanced Fertility Services & Treatments

At OU Health, you benefit from evidenced-based treatments, such as in-vitro fertilization (IVF), where our success rates exceed national averages and include strong pregnancy rates without multiples because we transfer the minimum number of embryos, based on guidelines set by the American Society for Reproductive Medicine.

You and your OU Health reproductive medicine care team members gain access to a full spectrum of advanced services and treatments using other assistive reproductive technologies such as:

• Donor insemination
• Embryo freezing
• Fertility preservation (egg freezing) for cancer conditions
• Frozen (cryopreserved) embryo transfer
• Hysterosalpingogram
• Intrauterine insemination, including donor sperm
• Intracytoplasmic sperm injection (ICSI)
• Intrauterine insemination
• Laparoscopic and hysteroscopic surgery
• Microdissection testicular sperm extraction (TESE)
• Microsurgical epididymal sperm aspiration (MESA)
• Oocyte (egg) freezing
• Ovulation induction
• Percutaneous epididymal sperm aspiration (PESA)
• Preimplantation genetic diagnosis
• Recipient / oocyte (egg) donation cycles
• Reproductive surgery
• Sperm freezing
• Surrogacy / gestational carrier cycles
• Testicular sperm aspiration (TESA)
• Testicular sperm extraction (TESE)

You also may pursue the opportunity to participate in clinical trials.

More Fertility Resources

Although many educational materials about fertility and reproductive medicine exist, you want the most accurate information from reputable sources, such as:

• American Society for Reproductive Medicine
• International Council on Fertility Information Dissemination
• Path2Parenthood, formerly American Fertility Association
• RESOLVE: The National Infertility Association

Other resources include DVDs Infertility Explained and Technostorks, as well as books such as The Conception Chronicles, Conquering Infertility, The Baby Trail: A Novel, The Right Fit: A Novel, Waiting for Daisy and A Few Good Eggs.

Clinical Research Trials

We understand that choosing to participate in a clinical trial is a very important decision that involves not only the patient, but their family, friends, and primary care physicians as well. All infertility physicians at the University of Oklahoma share the common goal of conducting clinical research and are dedicated to providing comprehensive care for their patients struggling with infertility.

Current Trials

Multi-center, parallel group, randomized controlled trial of modified natural versus programmed cycles for frozen embryo transfers and their association with preeclampsia and live births (NatPro)

• NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent)
• Each participant will have up to 3 FET cycles until live birth occurs, or the participant has no embryos available for transfer. The central hypothesis is that pregnancy resulting from a modified natural cycle FET will have a lower proportion of preeclampsia compared to that of a programmed FET

Evaluating the relationship between ovarian reserve and facial age as determined by computer software in non-infertile population

• To determine whether facial age is better correlated to anti-mullerian hormone (AMH) than a woman’s chronological age. We will look at serum anti-mullerian hormone level, which participants will have drawn at the OU Health Physicians Reproductive Medicine Clinic
• The patients will also complete a survey and have their photos taken on a tablet the day their blood is drawn and the facial image will be sent without any other patient identifiers to be analyzed by the artificial intelligence enhanced automated face age solutions
• Participating subjects will receive the data collected

Myo-inositol as an Adjuvant to Letrozole for Infertility in Polycystic Ovary Syndrome (MALI-PCOS): A randomized pilot trial

• This will be a prospective, double-blind randomized clinical trial of letrozole and placebo vs letrozole and inositols for up to 5 treatment cycles (spanning approximately 24 weeks) of ovulation induction or until pregnancy is achieved
• Subjects will be provided the supplement, Femara and progesterone blood testing as part of their participation

A Prospective, Multicenter, Single-arm, Feasibility Study of the AblaCare System in Transvaginal Ablation of Ovarian Tissue under ULTRAsound Visualization in Women with Infertility due to Polycystic Ovary Syndrome “ULTRA-US” Study

• May Health is developing an innovative treatment designed to restore ovulation
• Through targeted ovarian ablation, this one-time treatment aims to lower androgen production, which can often restore ovulation. Ovarian Rebalancing™ can be done conveniently at the physician’s office–no hormones necessary