Steven Chernausek, MD

  • Position: Assistant Professor, Department of Pediatrics, Diabetes Research Member

Biography

Steven Chernausek, MD and is the CHF Edith Kinney Gaylord Professor of Pediatrics at the University of Oklahoma College of Medicine. He was a pediatric endocrine fellow at the University of North Carolina at Chapel Hill where he was introduced to the insulin-like growth factors (IGFs) and the role those factors play in the control of somatic growth. Following fellowship, he moved to Cincinnati Children’s Hospital Medical Center and continued studies of human growth with specific reference to the actions of IGF-I. In 2007, he joined the faculty at the University of Oklahoma Health Science Center and became the first Director of the CMRI Pediatric Metabolic Research Program at the University of Oklahoma Health Sciences Center. The mission of the program is to improve the health of children with diabetes, obesity and related metabolic disorders. Dr. Chernausek’s current research is focused on how a pregnant woman’s physiological state affects the metabolic fate of her offspring. His resume lists more than 140 publications and includes the first description of IGF resistance due to IGF receptor gene defect, the results of clinical trials of rhIGF-I and rhGH in a variety of growth disorders, and the identification of novel mechanisms of metabolic programming involving microRNAs. He has served on the editorial boards of Endocrinology and Journal of Clinical Endocrinology and Metabolism and on the Sub-board of Endocrinology for the American Board of Pediatrics. He is a member of the American Pediatric Society, served on the Council for the Society for Pediatric Research and is a past president of the Pediatric Endocrine Society.

Email

Steven-Chernausek@ouhsc.edu

Additional Websites

Health Education
  • Graduate School
  • Fellowship, Pediatric Endocrinology University of North Carolina at Chapel Hill
    Chapel Hill, NC
  • Residency, Pediatrics University of Minnesota
    Minneapolis, MN
  • Doctor of Medicine University of Minnesota
    Minneapolist, MN
  • Undergraduate School
  • Bachelors, Biology Carleton College
    Northfield, MN
Research Interests:
  • Effects of maternal diabetes on offspring
  • Role of microRNAs in metabolism and diabetes
  • Type 2 diabetes in youth: prediction and prevention
  • Developmental origins of adult disease
  • Hormonal control of growth
Publications
  • A genetic approach to evaluation of short stature of undetermined cause 2018

    Lancet Diabetes Endocrinol. 2018 Jul;6(7):564-574. PubMed PMID: 29397377.

  • Offspring sex impacts DNA methylation and gene expression in placentae from women with diabetes during pregnancy 2018

    PLoS One. 2018;13(2):e0190698. PubMed PMID: 29470513; PubMed Central PMCID: PMC5823368.

  • Effects of maternal diabetes and fetal sex on human placenta mitochondrial biogenesis 2017

    Placenta. 2017 Sep;57:26-32. PubMed PMID: 28864016; PubMed Central PMCID: PMC5659203.

  • Relationship Between Parental Diabetes and Presentation of Metabolic and Glycemic Function in Youth with Type 2 Diabetes: Baseline Findings from the TODAY Trial 2016

    Diabetes Care. 2016 Jan;39(1):110-7. PubMed PMID: 26577415; PubMed Central PMCID: PMC4686846.

  • Lower resting energy expenditure and fat oxidation in Native American and Hispanic infants born to mothers with diabetes 2015

    J Pediatr. 2015 Apr;166(4):884-9. PubMed PMID: 25648295; PubMed Central PMCID: PMC4380761

  • IGF receptor gene variants in normal adolescents: effect on stature 2012

    European journal of endocrinology, 167(6), 777-81. PMID: 22972910. DOI: 10.1530/EJE-12-0565

  • IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation 2003

    N Engl J Med. 2003 Dec 4;349(23):2211-22. PubMed PMID: 14657428.

  • Structural similarities between human receptors for somatomedin C and insulin: analysis by affinity labeling 1981

    Biochemistry, 20(26), 7345-50. PMID: 6275879.