Gaston Ofman, MD

Biography

The Ofman laboratory works focuses on very early determinants of long-term preterm outcomes. Research is targeted at understanding bedside and laboratory environmental exposures that modulate the developing cardiopulmonary system offering a window of opportunity to improve the undesirable consequences of premature birth.

Dr. Ofman is specifically researching phenotype-specific disease determinants, from molecular alterations in mitochondrial function to genetic mutations or gene-by-environment interactions that leads to cardiopulmonary outcomes in newborns. He is also interested in finding specific physiologic predictors of bronchopulmonary dysplasia, a form of preterm pulmonary disease, and aligning those with laboratory findings. The laboratory hopes to develop combine molecular mechanisms with physiologic and bedside biomarkers hoping to identify early disease mechanisms and potential modifiable risk factors and therapeutic targets.

Email

gaston-ofman@ouhsc.edu

Publications

Research Interests:

• Accelerated senescence of preterm infants
• Redox Biology
• Cardiopulmonary outcomes of prematurity