Geroscience CoBRE

To expand research capacity overall and enhance the professional research skills of upcoming investigators in the field of aging and age-related disease, the Oklahoma Center for Geroscience and Healthy Brain Aging brings together multiple partners and resources in a Center of Biomedical Research Excellence (CoBRE).

Nationally Supported Geroscience Research

One of three program projects at Oklahoma Center for Geroscience and Healthy Brain Aging funded by the National Institutes of Health (NIH), the Geroscience CoBRE helps develop emerging research topics through a grant from the National Institute of General Medical Sciences (NIGMS). The CoBRE also provides early-career support to build professional skills that researchers need to successfully apply for an initial R01 grant-funded research project.

Learn more about geroscience emerging topics and early-career research support.

Geroscience CoBRE Core Services

In addition to six core services available through a partnership with Oklahoma Nathan Shock Center on Aging, the Oklahoma Center for Geroscience and Healthy Brain Aging in Oklahoma City provides three additional related core services to assist promising junior investigators (PJIs) who focus on research into aging and age-related diseases. CoBRE cores include:

  • Administrative services – Provides grant administration, recruitment, mentoring and statistics (ARMS); coordinates recruitment and replacement of researchers; oversees mentoring of investigators by senior faculty; provides biostatistical support that includes research design, data management and statistical analysis
  • Animal model development and behavioral analysis (AMD-BA) – Centralizes breeding, maintenance, phenotyping and behavioral characterization of animal models of aging and age-related chronic diseases; includes water maze and tissue bank
  • Molecular analysis and cellular imaging (MACI) – Offers instrumentation, services and training for rigorous analysis of structure and function through gene expression, gene regulation and imaging studies; includes photon and cranial window technique, slide preparation

When you become a researcher at Oklahoma Center for Geroscience and Healthy Brain Aging, you also may gain access to extensive research facilities and core services through the University of Oklahoma Health Sciences Center (OUHSC).

The Geroscience CoBRE offers four (4) positions for promising junior investigators (PJIs) to support the laboratory work of a qualified investigator (QI) who has not yet secured R01 funding. Positions include professional mentoring in a wide range of areas, with term lengths that may extend for up to three (3) years.

T32 Professional Research Training Opportunities

Early-career researchers may qualify for opportunities supported by a T32 research training grant at Oklahoma Center for Geroscience and Healthy Brain Aging. T32 training helps develop valuable research skills and includes benefits from professional mentorship.

Join Oklahoma’s Geroscience Professionals

As a clinician, educator or researcher working in the area of age-related disease, you’re encouraged to become a member of the Oklahoma Center for Geroscience and Healthy Brain Aging. Join our broad effort to better understand the aging process, reduce disease and improve quality of life as we all get older.

View our leadership team and find OU Health geroscience clinical faculty.

Contact us to learn how you can partner with Oklahoma Center for Geroscience and Healthy Brain Aging.

National Funding Support for Oklahoma

Oklahoma Center for Geroscience and Healthy Brain Aging is funded in part by an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health.

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