Yan Chen, PhD

  • Research Program: Geroscience
  • Position: College of Medicine, Department of Ophthalmology, Associate Professor
Health Education
  • Graduate School
  • Ophthalmology Vanderbilt University
    Nashville, TN
  • Biochemistry Emory University
  • Cell Biology and Developmental Biology
    Atlanta, GA
Research Interests:
  • mTOR; Aging
  • Age-related Degeneration
  • Retinal Pigmental Epithelium
  • Age-related Macular Degeneration
Publications
  • MTOR-initiated metabolic switch and degeneration in the retinal pigment epithelium 2020
  • Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epithelium 2018
  • Choroidal gammadelta T cells in protection against retinal pigment epithelium and retinal injury 2017
  • Subcellular distribution and activity of mechanistic target of rapamycin in aged retinal pigment epithelium 2014
  • Age-related retinopathy in NRF2-deficient mice 2011
  • Altered mTOR signaling in senescent retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010