Jeanie Tryggestad, MD

  • Position: Diabetes Research Member, Associate Professor, Department of Pediatrics

Biography

Dr. Tryggestad’s clinical research interests are on the impact of youth onset type 2 diabetes on complications. She is a Co-Principle Investigator for the NIH funded TODAY trial in Oklahoma and served on the Comorbidity Assessment Committee.

Dr. Tryggestad’s other research interest focus on the impact of maternal diabetes on the future cardiometabolic health of the offspring and the impact of obesity and diabetes on vascular function. She has been awarded grant through the NIH to understand the impact of maternal diabetes on miRNA expression and protein regulation in infants.

Dr. Tryggestad serves as the co-director of the type 2 diabetes comprehensive clinic in youth at Oklahoma Children’s Hospital OU Health. Her clinical interests are focused on type 1 and type 2 diabetes with special focus on Native American populations. She also serves as the director of the Turner Syndrome Clinic.

Email

Jeanie-Tryggestad@ouhsc.edu

Additional Websites

Health Education
  • Graduate School
  • Fellowship, Pediatric Endocrinology University of Oklahoma College of Medicine
    Oklahoma City, OK
  • Residency, General Pediatrics University of Oklahoma College of Medicine
    Oklahoma City, OK
  • Doctor of Medicine University of Oklahoma College of Medicine
    Oklahoma City, OK
  • University
  • Bachelor's Degree Oklahoma Christian University
    Oklahoma City, OK
Research Interests:
  • Type 2 diabetes in youth
  • Impact of maternal diabetes on fetal programming
  • Treatment Modalities in Youth Onset T2DM
  • Vascular Complications in Youth Onset T2DM
  • miRNA in Prediction of Beta-cell function and Microvascular Disease
  • Impact of Maternal Diabetes on Future Cardiometabolic Function in Offspring
  • Impact of Maternal Diabetes on Cellular Metabolism: Impact of miRNA
Publications
  • Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta 2021

    2021 Apr;89(5):1157-1163. doi: 10.1038/s41390-020-1060-x. Epub 2020 Jul 14. PubMed PMID: 32663836; PubMed Central PMCID: PMC7854929.

  • Long-Term Complications in Youth-Onset Type 2 Diabetes 2021

    2021 Jul 29;385(5):416-426. doi: 10.1056/NEJMoa2100165. PubMed PMID: 34320286.

  • Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study 2021

    2021 Sep 20;. doi: 10.1007/s00592-021-01796-6. [Epub ahead of print] PubMed PMID: 34542729.

  • Type 2 Diabetes in Youth: the Role of Early Life Exposures 2020

    2020 Aug 7;20(9):45. doi: 10.1007/s11892-020-01328-6. Review. PubMed PMID: 32767148.

  • Circulating adhesion molecules and associations with HbA1c, hypertension, nephropathy, and retinopathy in the Treatment Options for type 2 Diabetes in Adolescent and Youth study 2020

    2020 Sep;21(6):923-931. doi: 10.1111/pedi.13062. Epub 2020 Jul 2. PubMed PMID: 32501612; PubMed Central PMCID: PMC7877547.

  • Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study 2019

    2019 Nov;42(11):2143-2150. doi: 10.2337/dc19-0993. Epub 2019 Sep 9. PubMed PMID: 31501226; PubMed Central PMCID: PMC6804614.

  • Prevalence of arterial stiffness in adolescents with type 2 diabetes in the TODAY cohort: Relationships to glycemic control and other risk factors. J Diabetes Complications. 2018

    2018 Aug;32(8):740-745. DOI: 10.1016/j.jdiacomp.2018.05.013. Epub 2018 May 25. PubMed PMID: 29936086; PubMed Central PMCID: PMC6444355.

  • Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. 2016

    Clin Sci (Lond). 2016 Nov 1;130(21):1955-67. DOI: 10.1042/CS20160305. Epub 2016 Aug 25. PubMed PMID: 27562513; PubMed Central PMCID: PMC5516927.

  • Complications and comorbidities of T2DM in adolescents: findings from the TODAY clinical trial. J Diabetes Complications. 2015

    2015 Mar;29(2):307-12. DOI: 10.1016/j.jdiacomp.2014.10.009. Epub 2014 Oct 29. Review. PubMed PMID: 25468310; PubMed Central PMCID: PMC4333013.

  • Arterial compliance is increased in children with type 2 diabetes compared with normal-weight peers but not obese peers. 2013

    Pediatr Diabetes. 2013 Jun;14(4):259-66. DOI: 10.1111/pedi.12017. Epub 2013 Mar 5. PubMed PMID: 23458165; PubMed Central PMCID: PMC3665759.